Peptide Copper Tripeptide-3 oo iib ah oo kulul
Sharaxaadda Badeecada
- Suuqa daryeelka shakhsi ahaaneed ee adduunka, "daryeelka madaxa-sida-maqaarka" iyo "daalinta timaha ee sayniska" ayaa soo ifbaxay iyagoo ah qaybaha ugu kobaca badan ee ugu sarreeya. Hawlgallada dhaqameed ee ka hortagga timaha-daalinta badanaa waxay la yimaadaan caqabado macaamiisha, sida marxaladaha daadinta degdegga ah marka laga baxo ama qaab-dhismeedka oo liita. AHK-Cu (Copper Tripeptide-3) waa peptide calaamad biomimetic ah oo aad u sax ah. Si gaar ah loogu sameeyay waxay kicisaa koritaanka timaha, waxay kordhisaa wareegga koritaanka timaha, waxayna dib u habeysaa qaabka maqaarka ee madaxa, waxay si dhakhso ah u noqonaysaa xudunta tignoolajiyada ee serums-ka koritaanka timaha ee heerka sare ah, daawaynta madaxa, iyo khadadka daryeelka timaha ee ka hortagga gabowga.
- Bartilmaameedyada Bayoolojiga ee Aasaasiga ah: Unugyada Maqaarka ee Papilla (DPCs), Fibroblasts-ka Madaxa
- Codsiyada Muhiimka ah: Serums loogu talagalay ka hortagga timaha oo daata, tonics-ka hagaajinta madaxa, kor u qaadista koritaanka indhaha/shafka, iyo kareemada difaaca ee gabowga madaxa oo tayo sare leh.
- Hogaamiye ahaan alaab-qeybiyaha walxaha ceeriin ee peptide-ka firfircoon ee sare leh, waxaan bixinaa nadiifin sare, oo dufcad deggan AHK-Cu si aan uga caawinno astaantaada inay qabsato geeska tignoolajiyada suuqa daryeelka timaha ee sayniska.
Falanqaynta Aasaasiga ah
| Shay | Heerka Caadiga ah | Natiijo |
| Muuqaalka | Budada buluugga ah | Waafaqsan |
| Aqoonsiga ESI-MS | MW aragtiyeed: 415.12 | Waafaqsan |
| Nadiifnimo (HPLC) | ≥95.0% | 98.30% |
| Biyaha (KF) | ≤5.0% | 4.66% |
| Iyada oo leh⁺ Mawduuc | 8.0-16.0% | 12.13% |
| Mawduuca AHK | ≥65.0% | 70.13% |
| Ka kooban Koloriin (IC) | ≤10.0% | 8.59% |
| pH (1% Dareeraha Biyaha) | 6.0-8.0 | 7.52 |
| Milmida | ≥100mg/ml (H₂O) | Waafaqsan |
| Lead (mg/kg) | ≤10 |
|
| Arsenic (mg/kg) | ≤2 |
|
| Meerkuri (mg/kg) | ≤1 |
|
| Cadmium (mg/kg) | ≤5 |
|
| Wadarta tirada saxannada (cfu/g) | ≤1000 | Waafaqsan |
| Khamiirka iyo caaryada (cfu/g) | ≤100 | Waafaqsan |
Faa'iidooyinka
Iyadoo AHK-Cu ay ka tirsan tahay isla qoyska peptide-ka naxaasta ah sida peptide-ka dib-u-habaynta maqaarka ee caanka ah ee GHK-Cu (Copper Tripeptide-1), haddana is-dhexgalka Alanin Taxanaha peptide-ka wuxuu siinayaa xiriir aad u sarreeya oo isku xidhnaan ah qaab-dhismeedka timaha timaha iyo unugyada madaxa:
- Firfircoonaanta Unugyada Papilla ee Maqaarka iyo Kordhinta Marxaladda Anagen
Unugyada maqaarka ee papilla waxay u dhaqmaan sidii "xarunta taliska" ee nidaamisa dhumucda iyo koritaanka timaha. AHK-Cu waxay si weyn u kicisaa faafitaanka unugyadan, taasoo ka hortagaysa in timaha ay si degdeg ah u galaan marxaladda catagen (dib u gurashada). Iyadoo la dheereynayo kordhinta timaha. Marxaladda koritaanka (anagen), waxay yareysaa soo-baxa maalinlaha ah ee ka yimaada xididka.
- Kordhinta Isku-darka Matrix-ka Ka-baxsan Unugyada (ECM)
Gabowga madaxa ayaa horseeda yaraanta follicle-ka. AHK-Cu si wax ku ool ah ayay ugu dhiirigelisaa fibroblasts-ka madaxa inay sameeyaan Collagen iyo Elastin Nooca I. Tani waxay qarisaa unugyada maqaarka ee ku xeeran, iyadoo siinaysa "matrix anchoring" adag oo loogu talagalay xididdada timaha iyo ka hortagga daadinta jirka ee degdega ah.
- Yareynta Waxyaabaha Kiciya Timaha oo Daadanaya (DHT oo Yar oo Joojinaysa)
Qiimaynta In vitro waxay muujinaysaa in AHK-Cu ay muujinayso u janjeera xakamaynta 5-alpha reductase - ensaym-ka mas'uulka ka ah soo saarista Dihydrotestosterone (DHT), oo ah sababta ugu weyn ee ka dambaysa alopecia-da androgenetic. Waxay bixisaa beddel jilicsan oo aan dawo lahayn iyada oo aan abuurin iska caabin ama ku-tiirsanaan.
- Hagaajinta Microcirculation-ka Madaxa
Isku-dhafka naxaasta wuxuu kor u qaadaa muujinta arrimaha koritaanka endothelial-ka xididdada dhiigga, isagoo kicinaya shabakadda micro-capillary ee madaxa. Tani waxay si toos ah u siisaa oksijiin hodan ah oo aan kala go 'lahayn iyo nafaqooyin muhiim ah follicles-ka gaajaysan.
- Waxqabadka Timaha ee la xaqiijiyay
Baaritaannada unugyada isbarbardhigga ah, AHK-Cu waxay muujinaysaa waxtar aad u fiican oo lagu dedejinayo koritaanka unugyada epithelial-ka ee follicular, taasoo ka dhigaysa beddel caalami ah oo ammaan ah oo loogu talagalay kiciyeyaasha timaha ee kiimikada dhaqameed.
- Marxaladaha Dib-u-soo-celinta ama Daadinta Xag-jirka ah
Si ka duwan daawooyinka kale ee adag ee keeni kara cuncun deegaan, casaan, ama "shoog daadanaya" oo aad u weyn haddii la joojiyo, AHK-Cu waa mid gebi ahaanba la jaan qaadi kara noolaha, aan dhibsanayn, wuxuuna muujiyaa muuqaal badbaado oo heer sare ah.
Codsiga
- Serums-ka Bartilmaameedka Ka-hortagga Lumista Timaha ee Sare
Ku habboon geesi firfircoon oo ay weheliso kubbadaha duubista madaxa ama farsamooyinka hoos u dhigista, oo bartilmaameedsanaya timaha oo libdhaya iyo taajka khafiifiya.
- Ampoules Daaweynta Madaxa-Kalkaalisada
Waxaa loogu talagalay saloonno xirfadeed ama khadadka daryeelka caafimaadka, oo ku habboon isticmaalka daaweynta ka dib ama nidaamyada cirbadaha yar yar si loo dedejiyo soo kabashada xannibaadda madaxa iyo baraarugga follicle-ka.
- Kordhiyeyaasha Koritaanka Indhaha iyo Sunnayaasha
Iyada oo ka faa'iideysanaysa dabeecadeeda jilicsan ee aan xabka lahayn si loo sameeyo alaab nadiif ah, ammaan ah, oo si dhakhso leh u dheereysa indhaha.
